The Relative Information about Sodium Hyaluronate
Hyaluroan family is composed by a wide group of different molecular weight,the basilar unit of the polymer is disaccharide of β(1,4)-glucuronic acid-β(1,3)-N-Acetalglucosamine.It is part of the glycosaminoglycan family.
Hyaluronan is a stable molecule,with good flexibility and exceptional rheological properties.In vivo it is produced by hyaluronan synthase enzymes starting from activated nucleotide sugars(UDP-Glucuronic acid and UDP-N-Acetylglucosamine) and destroyed by hyaluronidases.
High Concentration of hyaluronan can be found in the umbilical cord,the synovial fluide between joints,in the vitreous body of the eye and in the skin.In the latter,it is possible to find 50% of the hyaluronan of all the human body.
Sodium Hyaluronate is the salt form of Hyaluronic Acid,a water-binding molecule that has the ability to fill the spaces between the connective fibers known as collagen and elastin.This ingredient hydrates the skin,allowing it to retain water and creating also a plumping effect.Sodium Hyaluronate has been used for moisturization and wound healing since its discovery in the 1930s.It consists of small molecules that penetrate the skin easily,and can hold up to 1,000 times their own weight in water.Since the skin naturally loses its water composition as it ages Hyluronic Acid and Sodium Hyaluronate can replace some of the water lost in the dermis,and potentially fight wrinkels and other signs of aging.
Sodium Hyaluronate is well known as the best natural moisturing agent.In early 1980s,the excellent moisturizing function of Sodium Hyaluronate started to be used in different cosmetic ingredients thanks to its unique film-forming and hydrating properties.
Technical Parameters:
| Product Type | Molecular Weight | Applications | Main Function |
| Cosmate®HA -XSMW | 20~100KDa | Wound Healing | It can penetrate in the dermis,promote skin absorption of nutrients,with strong wrinkles reduction,increasing skin elasticity,delay skin aging. |
| Cosmate®HA -VLMW | 100~600KDa | Long lasting moisturizing/anti-wrinkels | |
| Cosmate®HA -LMW | 600~1,100KDa | Deep Hydration | Longterm moisturizing action and works to sustain stable emulsion,with thickening effect. |
| Cosmate®HA -MMW | 1,100~1,600KDa | Daily Hydration | A smooth daily moisturizer,it nourishes and hydrates the skin with all day long efficacy. |
| Cosmate®HA -HMW | 1,600~2,000KDa | Lenitive/External hydration | It shapes a hydrating layer on skin surface,it maintains the barrier function and self-absorption capacity of the stratum corneum,it protects the skin from external agents,and it maintains skin smooth and moisture. |
| Cosmate®HA -XHMW | >2,000KDa | Film forming effect to prevents the TEWL |
